PT  - JOURNAL ARTICLE
AU  - A P Cope
AU  - A Jones
AU  - M Brozovic
AU  - M S Shafi
AU  - R N Maini
TI  - Possible induction of systemic lupus erythematosus by human parvovirus.
AID  - 10.1136/ard.51.6.803
DP  - 1992 Jun 01
TA  - Annals of the Rheumatic Diseases
PG  - 803--804
VI  - 51
IP  - 6
4099  - http://ard.bmj.com/content/51/6/803.short
4100  - http://ard.bmj.com/content/51/6/803.full
SO  - Ann Rheum Dis1992 Jun 01; 51
AB  - A 59 year old woman presented with an influenza-like illness preceding signs and symptoms strongly suggestive of systemic lupus erythematosus (SLE), which progressed over several months. Owing to these influenza-like symptoms, a viral cause of her illness was sought. Human parvovirus B19 serology was positive and antibodies to DNA were detected by two different methods. This patient is believed to be the first report of human parvovirus B19 infection coinciding with the onset of SLE. The evidence for B19 virus and the part it plays in autoimmunity and arthritis is discussed.