PT - JOURNAL ARTICLE AU - J A Casas AU - C P Subauste AU - G S Alarcón TI - A new promising treatment in systemic sclerosis: 5-fluorouracil. AID - 10.1136/ard.46.10.763 DP - 1987 Oct 01 TA - Annals of the Rheumatic Diseases PG - 763--767 VI - 46 IP - 10 4099 - http://ard.bmj.com/content/46/10/763.short 4100 - http://ard.bmj.com/content/46/10/763.full SO - Ann Rheum Dis1987 Oct 01; 46 AB - Twelve patients with systemic sclerosis according to American Rheumatism Association criteria were treated with intravenous 5-fluorouracil. Significant subjective and objective improvement occurred initially in the skin and subsequently in the involved viscera and vasculature. These preliminary results suggest that 5-fluorouracil may be an effective treatment for systemic sclerosis.