RT Journal Article
SR Electronic
T1 Cancer morbidity in rheumatoid arthritis.
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 128
OP 131
DO 10.1136/ard.43.2.128
VO 43
IS 2
A1 P Prior
A1 D P Symmons
A1 C F Hawkins
A1 D L Scott
A1 R Brown
YR 1984
UL http://ard.bmj.com/content/43/2/128.abstract
AB A consecutive series of 489 patients with rheumatoid arthritis seen at the centre was studied to determine their cancer morbidity. Overall the 36 cancers diagnosed in the series between 1964 and 1981 were not significantly in excess of the expected number, but there was a highly significant excess of tumours of the reticuloendothelial system. The excess was mainly due to 6 observed cases of lymphoma. We conclude that there is a highly significant association between rheumatoid arthritis and the subsequent development of lymphoproliferative malignancy in this series.