RT Journal Article
SR Electronic
T1 Circulating immune complexes in cutaneous and systemic vasculitis: clinicopathological correlations.
JF Annals of the Rheumatic Diseases
JO Ann Rheum Dis
FD BMJ Publishing Group Ltd and European League Against Rheumatism
SP 25
OP 29
DO 10.1136/ard.41.1.25
VO 41
IS 1
A1 Barratt, J
A1 Sindrey, M
A1 Summerly, R
A1 Aber, G M
A1 Naish, P
YR 1982
UL http://ard.bmj.com/content/41/1/25.abstract
AB A high incidence of raised levels of circulating immune complexes has found in a group of patients with idiopathic vasculitis. Serial measurements in 8 patients with systemic vasculitis showed a good correlation between clinical status and circulating immune complex levels. Some correlation existed between the constituents of circulating and tissue-bound complexes in 6 patients so studied. However, there was no correlation between apparent organ involvement and hypocomplementaemia and the levels of size of circulating immune complexes. It is concluded that the measurement of circulating immune complexes may be clinically useful in vasculitis, but that no direct evidence is yet available that they are pathogenetically related to those which are tissue-bound.