RT Journal Article SR Electronic T1 Prospective analysis of antiribonucleoprotein antibodies in systemic lupus erythematosus. JF Annals of the Rheumatic Diseases JO Ann Rheum Dis FD BMJ Publishing Group Ltd and European League Against Rheumatism SP 557 OP 559 DO 10.1136/ard.36.6.557 VO 36 IS 6 A1 B Bresnihan A1 R Grigor A1 G R Hughes YR 1977 UL http://ard.bmj.com/content/36/6/557.abstract AB A prospective analysis of 50 successive patients with systemic lupus erythematosus, seen over a 4-year period, has been completed. 336 sera were examined for the presence of antibody to ribonucleoprotein using a counterimmunoelectrophoresis assay. Antibody was present in the sera of 16% of patients and was detectable in about the same titre throughout the course of the disease. The presence of the antibody did not appear to identify a subgroup of lupus patients with individual clinical characteristics.