PT - JOURNAL ARTICLE AU - B Bresnihan AU - R Grigor AU - G R Hughes TI - Prospective analysis of antiribonucleoprotein antibodies in systemic lupus erythematosus. AID - 10.1136/ard.36.6.557 DP - 1977 Dec 01 TA - Annals of the Rheumatic Diseases PG - 557--559 VI - 36 IP - 6 4099 - http://ard.bmj.com/content/36/6/557.short 4100 - http://ard.bmj.com/content/36/6/557.full SO - Ann Rheum Dis1977 Dec 01; 36 AB - A prospective analysis of 50 successive patients with systemic lupus erythematosus, seen over a 4-year period, has been completed. 336 sera were examined for the presence of antibody to ribonucleoprotein using a counterimmunoelectrophoresis assay. Antibody was present in the sera of 16% of patients and was detectable in about the same titre throughout the course of the disease. The presence of the antibody did not appear to identify a subgroup of lupus patients with individual clinical characteristics.