eLetters

117 e-Letters

published between 2010 and 2013

  • Preemptive Treatment of Hepatitis B in Patients of Rheumatoid Arthritis and Spondyloarthritis Using Tumor Necrosis Factor-alpha Antagonist: an Individualised Management.
    James CC Wei

    Dear editor,

    We are writing in response to 'Kinetics of viral loads and risk of hepatitis B virus reactivation in hepatitis B core antibody-positive rheumatoid arthritis patients undergoing anti-tumor necrosis factor alpha therapy' by Lan, et al[1]. We performed a similar retrospective study in the rheumatoid arthritis and the spondyloarthritis patients comorbid with chronic hepatitis B treated by anti-tumor ne...

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  • Non-melanoma skin cancer risk in patients with rheumatoid arthritis on tumor necrosis factor inhibitors
    PRABHA RANGANATHAN

    Dear Editor,

    We read with interest the meta-analysis of registries and prospective observational studies conducted by Mariette and colleagues on the risk of malignancies in patients with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF) antagonists. (1) Their meta-analysis highlights the complexity surrounding this important clinical issue, when TNF antagonists are considered for patients with RA with...

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  • Is new evidence for the role of leptin playing in increasing risk of atherosclerosis in systemic lupus erythematosus?
    Wang-Dong Xu

    Wang-Dong Xu, Yu-Jing Zhang, Hai-Feng Pan, Dong-Qing Ye*

    Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, PR China;

    *Correspondence: Dong-Qing Ye, M.D, Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, PR China,

    E-mail: yd...

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  • Causality or Confounding by Indication: Do Statins Promote Development of Rheumatoid Arthritis? Comment on the Article by de Jong et al.
    Inge A. van den Oever

    Dear Editor,

    We read with interest the retrospective case-control study by de Jong et al.(1) The authors found an intriguing association between statin use and development of rheumatoid arthritis (RA). Some comments regarding the methodology and authors statements, may be appropriate.

    Evaluating treatment effects in observational studies can be problematic as prognostic factors influencing treatment decisions...

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  • Calcaneal enthesial reaction and "divots" lack specificity
    Bruce M. Rothschild

    Dear Editor,

    The study by Feydy and colleagues1 clearly evidences the importance of controls for assessment of the significance of clinical/radiologic observations/signs. Their eloquent study appropriately challenges the preconceived notion that enthesitis or enthesial reaction is an identifier for spondyloarthropathy2-5 and confirms the perceptions derived from studies of human skeletal collections.6,7 Those studies...

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  • A Case-control or a retrospective cohort study? Comment on the article by Martinez-Zamorra et al.
    Markus Bredemeier

    Dear Editor,

    I read with interest the study by Martinez-Zammora et al. (1), which reported an increased incidence of thrombotic events in patients with antiphospholipid syndrome with recurrent spontaneous abortion (APS-RSA group) in comparison with 3 different control groups. Although their conclusions seem to be valid, some comments may be appropriate.

    This study is labeled as 'case-control', but it is actual...

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  • Does Rheumatoid Synovitis Activity Vary During The Day? A sonographic and Doppler evaluation.
    Agnes Lhoste-Trouilloud

    Does Rheumatoid Synovitis Activity Vary During The Day? A sonographic and Doppler evaluation. A. Lhoste-Trouilloud1, B. Pereira2, M. Couderc3, S Mathieu3 , M. Soubrier3

    1 Radiology; 2DRCI; 3 Rheumatology Department, CHU Gabriel Montpied, Clermont-Ferrand, France

    Dear Editor,

    We read with interest the report of Semerano et al who describe a diurnal variation of power Doppler ultrasonography in the met...

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  • Association of malignancies with tumour necrosis factor inhibitors: real facts
    Srijit Das

    Dear Editor,

    We read with much interest the published article entitled 'Malignancies associated with tumour necrosis factor inhibitors in registries and prospective observational studies: a systematic review and meta-analysis' by Mariette et al [1]. Beyond any doubt, autoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus and psoriatic arthritis are associated with higher incidence of maligna...

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  • Comment on: Risk of septic arthritis in patients with rheumatoid arthritis and the effect of anti-TNF therapy
    Shigeki Momohara

    Dear Editor,

    We read with interest the recent article by Galloway et al. investigating septic arthritis (SA) in rheumatoid arthritis (RA) patients enrolled in the British Society for Rheumatology Biologics Register (BSRBR), who received anti tumour necrosis factor (anti-TNF) therapy.[1]
    The results of their evaluation of data from the BSRBR indicated that anti -TNF therapy for RA is associated with a doubling of t...

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  • Septic arthritis in patients with rheumatoid arthritis and the effects of anti-TNF therapy.
    David M Grennan

    Dear Editor,

    We are interested in the risk of sepsis in prosthetic joints after the use of biologic purposes for RA. We were therefore interested to read the study by 'Galloway et al (1). Galloway and colleagues have used data from the BSR biologics registry to examine the frequency of septic arthritis in anti - TNF treated patients and have found that both anti TNF therapy and previous prosthetic joints increase the...

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