eLetters

127 e-Letters

published between 2004 and 2007

  • Isolated cervical spine involvement in young patients with diffuse idiopathic skeletal hyperostosis
    Reuven Mader

    Dear Editor,

    The article by Gorman et al.[1], described three unusual features of diffuse idiopathic skeletal hyperostosis (DISH). One was the young age of the patients, the second was the familial occurrence, and the third was an isolated involvement of the cervical spine. We recently described a case of a young patient, 36 years of age, with isolated involvement of the cervical spine.[2] It was estimated that a p...

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  • OA, Atheroma and confusion
    Charles w Hutton

    Dear Editor,

    In response to the hypothesis article ‘Is progressive osteoarthritis an atheromatous vascular disease?’ [Conaghan, Hvanharanta, PA Dieppe Ann Rheum Dis V64 No11 Nov 2005 1539-1541].

    The hypothesis paper Atheroma and the Progression of Osteoarthritis of Conaghan et al.[1] confuses four questions. Is progressive OA related to local atheroma? Is it related to systemic atheroma? Do statins have an...

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  • Treatment of osteoarthritis
    shamsul A Bhuiyan,MD

    Dear Editor,

    Osteoarthritis can occur at almost any joint, osteoarthritis of the knee is the most common type. More than 10 million Americans have osteoarthritis of the knee. Most people affected are older than 45 years.[1]

    The published article by K L Bennel et al. lacks patient’s information like patient’s age, sex, weights, heights, and family history. In this article K L Bennel et al. concluded that p...

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  • Falls risk assessment in patients with rheumatoid arthritis: more to it than meets the eye
    Karen MJ Douglas

    Dear Editor,

    In their recent report, Armstrong and colleagues highlight the high prevalence of falls in patients with rheumatoid arthritis (RA)[1], show that falls increase with functional disability and antidepressant use, and comment that fracture prevention extends beyond the pharmacological treatment of osteoporosis. This concurs with current guidelines for the management of steroid induced osteoporosis[2], whi...

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  • Patient questionnaires in routine clinical care
    Yusuf Yazici

    Dear Editor

    I have read the article by Kvien et al. with great interest (1). I agree with their conclusion that PDA and other electronic media have a future in data collection not only in clinical trials but also possibly in routine clinical care, even in patients’ homes. However, I disagree with some of the points they raise.

    First, they state that patients were more satisfied with PDA than paper. I...

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  • Response to Drs Healy and Helliwell
    Martin Rudwaleit

    Dear Editor

    Our referral recommendations (1) for axial spondyloarthritis (SpA) that includes ankylosing spondylitis (AS) and early preradiographic forms of axial SpA were based on feasibility, costs, and effectiveness. Two screening parameters have been proposed: inflammatory back pain (IBP) and HLA-B27. According to data presented in an earlier publication (2) we assumed for IBP a sensitivity of 75% and a specific...

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  • Comment on Lack of efficacy of rituximab in refractory wegener's granulomatosis
    Daman M Langguth

    Dear Editor

    Aries et al. demonstrate in their study, the lack of response of granulomatous disease in Wegener's granulomatosis to rituximab. From my reading of the paper, this agent was given every fourth week. This is not how this agent is usually prescribed, ie usually given as weekly pulses for four weeks. Despite this, Bcell numbers were depleted in the peripheral blood, though I would doubt at this low dose...

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  • Pre-treatment screening takes place before anti-TNF is prescribed
    Harald Erwin Vonkeman

    Dear Editor

    In their article: Haematopoietic malignancies in rheumatoid arthritis: lymphoma risk and characteristics after exposure to tumour necrosis factor antagonists (and likewise in their subsequent article: Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonists) Askling et al. compare occurrence rates for malignancies between different cohorts...

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  • Whiplash a systemic disease?
    Jerrold M. Gorski

    Dear Editor,

    Dr Ferrari has suggested that Whiplash Associated Disorders (WAD), is a systemic illness in the September Annals of Rheumatic Disesases[1], rather than an anatomically defineable lesion. They correctly quote that in 90% of patients with WAD no pathology can be found. Dr Ferrari reaches his conclusion from the acute subjective symptoms that describes involvement of multiple systems. It is not too surpr...

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  • Author's reply to: Expensive antirheumatic drugs
    Nick Bansback

    Dear Editor

    We very much welcome the thoughts of Drs Geborek and Saxne on our recent article,[1] and agree that a scientific approach should be taken to the synthesis of evidence in decision models. Our analysis is not the last word but rather the first decision analysis of adalimumab. The contention stems from the limitations in the evidence base. In this regard, to wait for all the evidence to be collected (possibly m...

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