eLetters

117 e-Letters

published between 2010 and 2013

  • Usefulness of ultrasonography in the diagnosis of gout: a meta-analysis
    Sylvain Mathieu

    Dear Editor,

    In an article published in Annals of the Rheumatic Diseases, Chowalloor et al. suggested, based on a literature review, that ultrasonography (US) is a promising tool which could be used in the diagnosis and management of gout [1]. In this letter, we wish to add further data to the Chowalloor et al. conclusion. We have performed a meta-analysis (up to July 2012) to investigate the frequency of ultrasonograph...

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  • Strontium and cardiovascular events
    Mark J Bolland

    Dear Editor,

    In the report of their trial of strontium ranelate in knee osteoarthritis, Reginster and colleagues state that "Strontium ranelate was well tolerated" and that "The safety profile of strontium ranelate was satisfactory, in line with knowledge of this agent" (1). However, contemporaneously, the European Medicines Agency recommended that the use of strontium ranelate be restricted because it increased the r...

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  • Systemic literature review of the performance of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis. Good news of debatable significance
    henning zeidler

    Dear Editor,

    Radner and colleagues report a systematic literature search analysing the numerous articles and conference proceedings which examined the performance of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis (RA) (1). The comprehensive evaluation identified if the 2010 criteria were correctly applied as suggested in the original publication, explored the performance of the criteria according...

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  • Associations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: data from CHECK, a cohort study of early osteoarthritis
    Harry Sprot

    Dear Editor,

    Associations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: data from CHECK, a cohort study of early osteoarthritis I read with interest this paper by Van Spil et al examining further the osteoarthritis(OA) biomarker CTX-II (C-terminal telopeptide of type II collagen) and note the suspicions of the authors tying this marker to bone metabolism[1]. High correlation wi...

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  • Patients with non-Jo-1 anti-RNA-synthetase autoantibodies have worse survival than Jo-1 positive patients
    Baptiste Hervier
    Dear Editor,

    We read with interest the manuscript by Aggarwal et al. entitled “Patients with non-Jo-1 anti-RNA-synthetase autoantibodies have worse survival than Jo-1 positive patients” 1. This large cohort study provides important information on outcomes for patients with antisynthetase syndrome (ASS), based on the specificity of the anti-RNA-synthetase autoantibody subtypes. Interestingly, the authors decided to include patie...

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  • The Reasons of Higher NT-proBNP Depend On Very Different Conditions
    Mehmet Aydogan

    Dear Editor,

    We read the article ''N-terminal pro-brain-type natriuretic peptide (NT-pro-BNP) and mortality risk in early inflammatory polyarthritis (IP): results from the Norfolk Arthritis Registry (NOAR).'' by Mirjafari et al with interest(1). The authors aimed to measure serum NT-pro-BNP levels in a large, well characterised inception cohort of patients with early IP and to examine baseline association of NT-pr...

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  • Anaemia to predict radiographic progression in Rheumatoid Arthritis
    Hanna W. van Steenbergen

    Dear Editor,

    The severity of rheumatoid arthritis (RA) is highly variable between patients and currently known risk factors explain only part of this variance.(1) Much research is dedicated to identify additional new risk factors. Such factors may shed light on the processes underlying progression of RA and many risk factors together may enable risk stratification and individualized treatment of RA.

    With...

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  • PGI2-induced Th17 cells differentiation in connective tissue disease: a comment
    He Jianguo

    Dear Editor

    We read with interest the study conducted by Truchetet and colleagues on the regulation of PGI2 in Th17 cells differentiation in systemic sclerosis (SSc). Actually, previous in vitro studies have found that synthetic PGI2 enhanced Th17 cells differentiation1. Zhou et al2 has also demonstrated that PGI2 induced Th17 cells differentiation through modulating the ratio of IL-23/IL-12 in a mouse model of experim...

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  • Response to comments by Clockaerts and colleagues
    Daniel L. Riddle

    Dear Editor,

    We thank Clockaerts and colleagues for their thoughtful commentary on our paper and will address a number of their comments. They expressed concern regarding lack of verification of our data related to statin use, duration of use, and dosage, and indicated these data were based on self- report. While we acknowledged in our paper[1] that we did not have dosage data, the verification was that participants...

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  • Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial
    Claire-Louise Murphy

    Dear Editor,

    We read with interest the paper regarding Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo- controlled trial. We note the exclusion criteria included secondary knee osteoarthritis. On review of the results section it appears that many of the patients both the randomised and the intention to treat groups e.g. the stronti...

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