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Osteoarthritis
Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis

Authors

  • Reem Assi Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Chahrazad Cherifi Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium Glycobiology Cell Growth Tissue Repair and Regeneration Research Unit, Gly-CRRET, Univ Paris Est Créteil, Créteil, France PubMed articlesGoogle scholar articles
  • Frederique M.F. Cornelis Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Qiongfei Zhou Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Lies Storms Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Sofia Pazmino Development and Regeneration, Skeletal Biology and Engineering Research Centre, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Rodrigo Coutinho de Almeida Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Ingrid Meulenbelt Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands Integrated research on Developmental determinants of Ageing and Longevity (IDEAL), Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Rik J. Lories Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium Division of Rheumatology, University Hospitals Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Silvia Monteagudo Development and Regeneration, Skeletal Biology and Engineering Research Center, Laboratory of Tissue Homeostasis and Disease, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Silvia Monteagudo; silvia.monteagudo{at}kuleuven.be; Dr Chahrazad Cherifi; cherifichahrazad{at}gmail.com
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Citation

Assi R, Cherifi C, Cornelis FM, et al
Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis
Annals of the Rheumatic Diseases 2023;82:963-973.

Publication history

  • Received December 19, 2022
  • Accepted March 7, 2023
  • First published March 16, 2023.
Online issue publication 
June 12, 2023

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© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.