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Response to: ‘Comparative analysis of synovial inflammation after SARS-CoV-2 infection’ by Alivernini et al
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  1. María-del-Carmen López-González1,
  2. Vega Jovani1,
  3. Esperanza Merino2,
  4. Paloma Vela1,3,
  5. Mariano Andrés1,3
  1. 1 Seccion de Reumatologia, Hospital General Universitario de Alicante, Alicante, Spain
  2. 2 Unidad de Enfermedades Infecciosas, Hospital General Universitario de Alicante, Alicante, Spain
  3. 3 Departamento de Medicina Clínica, Universidad Miguel Hernandez de Elche, Elche, Spain
  1. Correspondence to Dr Mariano Andrés, Seccion de Reumatologia, Hospital General Universitario de Alicante, Alicante 03010, Spain; drmarianoandres{at}gmail.com

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Few studies have described so far the occurrence of arthritis in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).1 For this reason, we read with great interest the report by Alivernini et al 2 where they present two cases of polyarthritis in the context of a SARS-CoV-2 infection, with an exhaustive study of synovial tissue. In the immunohistochemical study of both biopsies, they observed inflammatory infiltrates mostly composed of CD3+, CD138+ and CD68+ cells. Furthermore, in the patient with rheumatoid arthritis, case 2, they also detected CD20+ cells. The study of synovial tissue in the context of SARS-CoV-2 arthritis is of …

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