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Clinical characteristics and outcomes of patients with COVID-19 and rheumatic disease in China ‘hot pot’ versus in US ‘hot pot’: similarity and difference
  1. Jun Zhao1,
  2. Rongrong Pang1,2,
  3. Jian Wu1,
  4. Yanju Guo1,
  5. Yang Yang1,
  6. Libo Zhang1,2,
  7. Xinyi Xia1,3,4
  1. 1 COVID-19 Research Center, Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu 210002, China
  2. 2 Department of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, Jiangsu 210003, China
  3. 3 Department of Laboratory Medicine & Blood Transfusion, Wuhan Huoshenshan Hospital, Wuhan, Hubei 430100, China
  4. 4 Joint Expert Group for COVID-19, Wuhan Huoshenshan Hospital, Wuhan, Hubei 430100, China
  1. Correspondence to Professor Xinyi Xia, Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu 210002, China; xiaxynju{at}163.com

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We read with great interest the article by D’Silva et al concerning clinical characteristics and outcomes of patients with COVID-19 and rheumatic disease.1 In this study, the authors mentioned that patients with and without rheumatic disease had similar symptoms and laboratory findings, but those with rheumatic disease were more likely to require mechanical ventilation.

We analysed our data of 3059 patients with confirmed COVID-19, including 29 cases in combination with rheumatic diseases from Huoshenshan Hospital in Wuhan, which was a ‘hot spot’ of COVID-19 in China, from 4 February 2020 to 9 April 2020. There were 15 rheumatoid arthritis, 5 systematic lupus erythematosus, 1 Rhupus, 2 myasthenia gravis, 1 Sjögren’s syndrome, 1 ankylosing spondylitis, 1 dermatomyositis, 1 autoimmune liver disease and 2 undifferentiated connective tissue disease cases (figure 1). The study population encompassed 4 men and 25 women, with median age of 61 years. Twenty-one patients presented with cough, 21 patients had fatigue, 3 had diarrhoea, 14 had varying degrees of difficulty in breathing and fever was observed in all cases.

Figure 1

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Footnotes

  • JZ, RP and JW contributed equally.

  • Contributors JZ and RP conducted data analysis and wrote the manuscript. LZ contributed with comments during the writing. JW, YG and YY conducted data analysis. XX and LZ conceived the study.

  • Funding Key Foundation of Wuhan Huoshenshan Hospital (2020[18]), Key Research & Development Program of Jiangsu Province (BE2018713), Medical Innovation Project of Logistics Service (18JS005).

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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