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Ultrasonographic damages of major salivary glands are associated with cryoglobulinemic vasculitis and lymphoma in primary Sjogren’s syndrome: are the ultrasonographic features of the salivary glands new prognostic markers in Sjogren's syndrome?
  1. Guillaume Coiffier1,
  2. Amélie Martel2,
  3. Jean-David Albert1,
  4. Alain Lescoat3,
  5. Aurore Bleuzen4,
  6. Aleth Perdriger5,
  7. Michel De Bandt6,
  8. François Maillot2
  1. 1 Rheumatology Department, CHU Rennes, Rennes, France
  2. 2 Internal Medicine, CHRU Tours, Tours, France
  3. 3 Internal Medicine, CHU South Hospital, Rennes, France
  4. 4 Medical Imaging, CHRU Tours, Tours, France
  5. 5 Rhumatologie, Centre Hospitalier, Rennes, France
  6. 6 Rheumatology Department, University Hospital Martinique, Fort de France, France
  1. Correspondence to Dr Guillaume Coiffier, Rhumatologie, CHU de RENNES, 35000 Rennes, France; guillaume.coiffier{at}

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We read with great interest the new ultrasound scoring system of salivary glands for primary Sjogren’s syndrome (pSS) developed by Outcome Measures in Rheumatology (OMERACT) and recently reported by Jousse-Joulin et al .1 The salivary gland ultrasound (SGUS) is a simple, non-irradiating, non-expensive and accessible assessment tool. Several previous SGUS scoring systems have been proposed so far, but not all of them take into account every pathological features, especially in the parotid gland (such as hyperechoic bands) for the diagnosis of pSS. The lack of consensus between each of these SGUS scoring systems also had a negative impact on the reproducibility of the examination so far. By offering an updated consensual classification, the OMERACT initiative therefore constitutes an undeniable progress for the diagnosis of pSS.

Recently, in a multicentre prospective study of 97 patients referred for clinical sicca syndrome (39 pSS and 22 secondary Sjogren’s syndrome (sSS) according to American-European Consensus Group (AECG) criteria in comparison with 36 controls), we …

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