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How to communicate in science
  1. Lars Klareskog1,
  2. Anca Irinel Catrina1,
  3. Camilla Svensson2,
  4. Vivianne Malmstrom1
  1. 1Rheumatology Unit, Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden
  2. 2Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
  1. Correspondence to Professor Lars Klareskog, Rheumatology, Karolinska Institutet, Stockholm 171 76, Sweden; lars.klareskog{at}

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We have read the editorial from Toes and Pisetsky1 and the letter from Holmdahl2 concerning the role of ACPA in the pathogenesis of RA.

With regards to the editorial, we appreciate the comments on how methodological hurdles may impact the interpretation of functional data. We like to add to this discussion that we have recently published data using new extensively characterised monoclonal ACPAs3 4 and new …

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