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Response to: ‘Knee osteoarthritis and bisphosphonates: Could BCP crystals be the missing link?’ by Murphy et al
  1. Willem Lems
  1. Department of Rheumatology, VU University Medical Center, Amsterdam 1007MB, The Netherlands
  1. Correspondence to Willem Lems, Department of Rheumatology, VU University Medical Center, Amsterdam 1007MB, The Netherlands; wf.lems{at}vumc.nl

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I read with great interest the letter from Murphy and McCarthy1: ‘knee osteoarthritis and bisphosphonates: could BCP crystals be the missing link?’.1

I recently gave comments on two case-control studies,2 in which the need for a total knee prosthesis was around 25% lower in bisphosphonate (BP) users than in controls.3 4 What could be the explanation? It could …

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