Statistics from Altmetric.com
Raynaud’s phenomenon (RP) manifests as episodic vasospasm of the extremities (hands and feet) in response to cold exposure. RP can be primary (idiopathic) or secondary to underlying disease such as systemic sclerosis (SSc). Attacks of RP are often associated with digital colour changes reflecting local tissue perfusion and oxygenation. RP results in pain, numbness, impaired function and reduced quality of life.1 2 The obliterative vasculopathy of SSc can result in digital ulceration. Diagnostic delay of secondary RP remains a major unmet need. The time between the onset of RP and emergence of the first non-RP symptom can be over 5 years.3 This contributes to delay in diagnosis; with >25% of women not diagnosed with SSc for 10 years after the emergence of RP.4
Against this background, Scleroderma Raynaud’s UK (SRUK) led an initiative to devise …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.