Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis

Christopher P Denton; Voon H Ong; Shiwen Xu; Haiyin Chen-Harris; Zora Modrusan; Robert Lafyatis; Dinesh Khanna; Angelika Jahreis; Jeffrey Siegel; Thierry Sornasse

doi:10.1136/annrheumdis-2018-213031

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Basic and translational research

Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis

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Cite this article as:: Denton CP, Ong VH, Xu S, et al

Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis

Annals of the Rheumatic Diseases 2018;77:1362-1371.

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