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Response to: ‘Pitfalls of antinuclear antibody detection in systemic lupus erythematosus: the positive experience of a national multi-center study’ by Pregnalato et al
  1. David S Pisetsky1,
  2. Diane M Spencer1,
  3. Peter E Lipsky2,
  4. Brad H Rovin3
  1. 1Department of Medicine and Immunology, Duke University Medical Center and Medical Research Service, Veterans Administration Medical Center, Durham, North Carolina, USA
  2. 2RILITE Research Institute, Charlottesville, Virginia, USA
  3. 3Division of Nephrology, Department of Internal Medicine, Ohio State University, Wexner Medical Center, Columbus, Ohio, USA
  1. Correspondence to Dr David S Pisetsky, Department of Medicine and Immunology, Duke University Medical Center, Durham, NC 27705, USA; david.pisetsky{at}duke.edu

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We appreciate the comments by Pregnolato et al1 on our original paper2 and subsequent correspondence in the journal.3 4 The data presented are very interesting and suggest that, under certain circumstances, results of antinuclear antibody (ANA) testing with samples from patients …

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