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We read with great interest the study published by Moltó et al on the impact of concomitant fibromyalgia (FM) on tumor necrosis factor (TNF) alpha blockers’ effectiveness in axial spondyloarthritis (axSpA).1 Indeed, this is a challenging problem in daily practice, especially considering the difficulties in differentiating enthesitis and FM symptoms.2 Therefore, we would like to raise some issues that need clarification in order to better understand the relevance of the study.
In the published paper, data on the history of antidepressant, third-ladder analgesic and nonsteroidal anti-inflammatory drug (NSAID) intake in patients enrolled are extensively reported. The results indicate that the use of …
Footnotes
Contributors AA and RS equally contributed to writing the letter. GV conceptualised and critically revised the letter.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Not required.
Provenance and peer review Not commissioned; internally peer reviewed.