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Clinical and epidemiological research
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MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank

Authors

  • Xue Li Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Xiangrui Meng Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Athina Spiliopoulou Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Maria Timofeeva Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Medical Research Council, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Wei-Qi Wei Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Aliya Gifford Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Xia Shen Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Yazhou He Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK West China School of Medicine, West China Hospital, Sichuan University, Sichuan, China PubMed articlesGoogle scholar articles
  • Tim Varley Public Health and Intelligence, NHS National Services Scotland, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Paul McKeigue Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Ioanna Tzoulaki Department Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK MRC-PHE Centre for Environment, School of Public Health, Imperial College London, London, UK Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece PubMed articlesGoogle scholar articles
  • Alan F Wright Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Peter Joshi Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Joshua C Denny Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Harry Campbell Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Evropi Theodoratou Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Xue Li, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH4 2XU, UK; xue.li{at}ed.ac.uk
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Citation

Li X, Meng X, Spiliopoulou A, et al
MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank
Annals of the Rheumatic Diseases 2018;77:1039-1047.

Publication history

  • Received October 13, 2017
  • Revised January 12, 2018
  • Accepted January 21, 2018
  • First published February 6, 2018.
Online issue publication 
June 12, 2018

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/