Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

Francesco Ciccia; Giuliana Guggino; Aroldo Rizzo; Riccardo Alessandro; Michele Maria Luchetti; Simon Milling; Laura Saieva; Heleen Cypers; Tommaso Stampone; Paola Di Benedetto; Armando Gabrielli; Alessio Fasano; Dirk Elewaut; Giovanni Triolo

doi:10.1136/annrheumdis-2016-210000

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Basic and translational research

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Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

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Francesco Ciccia Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, University of Palermo, Palermo, Italy PubMed articles Google scholar articles
Giuliana Guggino Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, University of Palermo, Palermo, Italy PubMed articles Google scholar articles
Aroldo Rizzo UOC di Anatomia Patologica, Ospedali riuniti villa Sofia-Cervello, Palermo, Italy PubMed articles Google scholar articles
Riccardo Alessandro Dipartimento di Biopatologia e Biotecnologie Mediche, Università di Palermo, Palermo, Italy PubMed articles Google scholar articles
Michele Maria Luchetti Istituto di Clinica Medica Generale, Ematologia ed Immunologia Clinica, Università Politecnica delle Marche, Ancona, Italy PubMed articles Google scholar articles
Simon Milling Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Laura Saieva Dipartimento di Biopatologia e Biotecnologie Mediche, Università di Palermo, Palermo, Italy PubMed articles Google scholar articles
Heleen Cypers Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center, Ghent University, Belgium Department of Rheumatology, Ghent University, Ghent University Hospital, Ghent, Belgium PubMed articles Google scholar articles
Tommaso Stampone UOC di Anatomia Patologica, Ospedali riuniti villa Sofia-Cervello, Palermo, Italy PubMed articles Google scholar articles
Paola Di Benedetto Division of Rheumatology, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, L'Aquila, Italy PubMed articles Google scholar articles
Armando Gabrielli Dipartimento di Biopatologia e Biotecnologie Mediche, Università di Palermo, Palermo, Italy PubMed articles Google scholar articles
Alessio Fasano Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Center for Celiac Research and Treatment, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articles Google scholar articles
Dirk Elewaut Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center, Ghent University, Belgium Department of Rheumatology, Ghent University, Ghent University Hospital, Ghent, Belgium PubMed articles Google scholar articles
Giovanni Triolo Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, University of Palermo, Palermo, Italy PubMed articles Google scholar articles

Correspondence to Professor Giovanni Triolo, Department of Internal Medicine, Division of Rheumatology, Piazza delle Cliniche 2, Palermo 90127, Italy; giovanni.triolo{at}unipa.it

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Citation

Ciccia F, Guggino G, Rizzo A, et al

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

Annals of the Rheumatic Diseases 2017;76:1123-1132.

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October 31, 2019

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