Article info

Extended report
Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

Authors

  • Wang Hui MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), Musculoskeletal Research Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • David A Young MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), Musculoskeletal Research Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Andrew D Rowan MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), Musculoskeletal Research Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Xin Xu Biomedicine Biobank, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Tim E Cawston MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), Musculoskeletal Research Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Carole J Proctor MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), Musculoskeletal Research Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK Newcastle University Institute for Ageing, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Carole Proctor, MRC/Arthritis Research UK Centre for Integrated research into Musculoskeletal Ageing (CIMA), Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK; carole.proctor{at}ncl.ac.uk
View Full Text

Citation

Hui W, Young DA, Rowan AD, et al
Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

Publication history

  • Received July 16, 2014
  • Revised October 20, 2014
  • Accepted November 15, 2014
  • First published December 4, 2014.
Online issue publication 
October 25, 2017

Article Versions

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

    Files in this Data Supplement:

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.