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Risk of vascular disease with gout: overadjustment of the statistical analyses?
  1. Caroline M van Durme1,2,
  2. Bart Spaetgens1,
  3. Annelies Boonen1,
  4. Frank de Vries3
  1. 1Department of Internal Medicine, Maastricht University Medical Centre+, Maastricht, The Netherlands
  2. 2Service de Rhumatologie, Centre hospitalier Universitaire de Liège, Belgium
  3. 3Department of Clinical Pharmacy & Toxicology, Maastricht University Medical Centre+, Maastricht, The Netherlands
  1. Correspondence to Dr Caroline M van Durme, Department of Internal Medicine/Rheumatology, Maastricht University Medical Centre, P. Debyelaan 25, Maastricht 6229 HX, The Netherlands; carolinevd{at}

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An increase of 6% in the risk of vascular disease among men with gout (adj. HR 1.06 95% CI 1.01 to 1.12) and of 25% among women with gout (adj. HR 1.25 95%CI 1.15 to 1.35) was reported when analysing data of the world's largest primary care database, …

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