A randomised, double-blind, parallel-group study of the safety and efficacy of subcutaneous tocilizumab versus intravenous tocilizumab in combination with traditional disease-modifying antirheumatic drugs in patients with moderate to severe rheumatoid arthritis (SUMMACTA study)

Gerd R Burmester; Andrea Rubbert-Roth; Alain Cantagrel; Stephen Hall; Piotr Leszczynski; Daniel Feldman; Madura J Rangaraj; Georgia Roane; Charles Ludivico; Peng Lu; Lucy Rowell; Min Bao; Eduardo F Mysler

doi:10.1136/annrheumdis-2013-203523

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Clinical and epidemiological research

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A randomised, double-blind, parallel-group study of the safety and efficacy of subcutaneous tocilizumab versus intravenous tocilizumab in combination with traditional disease-modifying antirheumatic drugs in patients with moderate to severe rheumatoid arthritis (SUMMACTA study)

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	Abstract	Full	Pdf
Jul 2013	146	1	31
Aug 2013	1609	288	536
Sep 2013	1722	279	480
Oct 2013	882	275	286
Nov 2013	721	149	184
Dec 2013	1830	166	320
Jan 2014	990	180	333
Feb 2014	503	114	234
Mar 2014	496	126	164
Apr 2014	326	137	162
May 2014	270	113	126
Jun 2014	327	124	124
Jul 2014	233	100	86
Aug 2014	178	81	79
Sep 2014	215	83	124
Oct 2014	230	110	112
Nov 2014	187	92	96
Dec 2014	151	67	73
Jan 2015	215	95	137
Feb 2015	222	105	117
Mar 2015	177	65	72
Apr 2015	139	63	64
May 2015	127	72	72
Jun 2015	114	50	72
Jul 2015	110	65	51
Aug 2015	104	64	52
Sep 2015	134	73	80
Oct 2015	105	45	74
Nov 2015	121	59	80
Dec 2015	139	69	69
Jan 2016	132	56	76
Feb 2016	109	51	48
Mar 2016	109	74	84
Apr 2016	177	60	87
May 2016	133	51	81
Jun 2016	99	48	70
Jul 2016	105	37	57
Aug 2016	118	58	70
Sep 2016	108	41	51
Oct 2016	91	51	48
Nov 2016	114	57	64
Dec 2016	88	47	31
Jan 2017	130	51	65
Feb 2017	43	47	53
Mar 2017	41	147	62
Apr 2017	24	88	56
May 2017	28	75	48
Jun 2017	64	106	40
Jul 2017	160	103	55
Aug 2017	196	123	51
Sep 2017	149	93	50
Oct 2017	152	89	87
Nov 2017	160	72	53
Dec 2017	93	51	26
Jan 2018	144	94	44
Feb 2018	151	67	48
Mar 2018	199	97	48
Apr 2018	150	91	49
May 2018	127	75	32
Jun 2018	144	74	29
Jul 2018	125	66	30
Aug 2018	106	58	30
Sep 2018	125	82	34
Oct 2018	99	60	30
Nov 2018	92	62	22
Dec 2018	83	57	25
Jan 2019	110	88	36
Feb 2019	88	78	26
Mar 2019	98	70	37
Apr 2019	59	41	22
May 2019	64	52	26
Jun 2019	57	51	34
Jul 2019	67	54	46
Aug 2019	52	42	23
Sep 2019	66	46	26
Oct 2019	77	66	55
Nov 2019	62	41	41
Dec 2019	57	43	21
Jan 2020	82	64	27
Feb 2020	71	46	35
Mar 2020	131	99	53
Apr 2020	84	51	46
May 2020	92	52	69
Jun 2020	44	42	46
Jul 2020	40	30	17
Aug 2020	55	45	35
Sep 2020	84	57	30
Oct 2020	93	63	59
Nov 2020	105	76	36
Dec 2020	89	50	22
Jan 2021	72	54	34
Feb 2021	70	45	31
Mar 2021	60	52	39
Apr 2021	41	32	24
May 2021	87	60	28
Jun 2021	32	32	35
Jul 2021	31	30	36
Aug 2021	60	59	44
Sep 2021	58	58	22
Oct 2021	89	50	42
Nov 2021	67	52	62
Dec 2021	65	40	27
Jan 2022	52	39	23
Feb 2022	57	49	22
Mar 2022	61	46	33
Apr 2022	103	74	24
May 2022	76	60	46
Jun 2022	70	56	16
Jul 2022	64	50	26
Aug 2022	65	49	25
Sep 2022	78	62	19
Oct 2022	82	67	35
Nov 2022	88	67	11
Dec 2022	54	44	11
Jan 2023	106	87	22
Feb 2023	88	74	11
Mar 2023	96	75	21
Apr 2023	41	34	7
May 2023	63	45	27
Jun 2023	42	28	12
Jul 2023	49	39	21
Aug 2023	78	52	27
Sep 2023	111	101	16
Oct 2023	246	220	35
Nov 2023	309	282	14
Dec 2023	85	66	33
Jan 2024	74	63	33
Feb 2024	111	52	15
Mar 2024	84	64	91
Total	21883	9725	8292

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