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Basic and translational research
Extended report
Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis

Authors

  • Michal Tomcik Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany First Faculty of Medicine, Department of Rheumatology, Institute of Rheumatology, Charles University in Prague, Prague, Czech Republic PubMed articlesGoogle scholar articles
  • Pawel Zerr Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany PubMed articlesGoogle scholar articles
  • Jana Pitkowski Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany PubMed articlesGoogle scholar articles
  • Katrin Palumbo-Zerr Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany PubMed articlesGoogle scholar articles
  • Jérôme Avouac Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany Rheumatology A Department and INSERM U1016 Cochin Hospital, Paris Descartes University, Paris, France PubMed articlesGoogle scholar articles
  • Oliver Distler Center of Experimental Rheumatology and Zurich Center of Integrative Human Physiology, University Hospital, Zurich, Switzerland PubMed articlesGoogle scholar articles
  • Radim Becvar First Faculty of Medicine, Department of Rheumatology, Institute of Rheumatology, Charles University in Prague, Prague, Czech Republic PubMed articlesGoogle scholar articles
  • Ladislav Senolt First Faculty of Medicine, Department of Rheumatology, Institute of Rheumatology, Charles University in Prague, Prague, Czech Republic PubMed articlesGoogle scholar articles
  • Georg Schett Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany PubMed articlesGoogle scholar articles
  • Jörg H Distler Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Michal Tomcik, First Faculty of Medicine, Department of Rheumatology, Institute of Rheumatology, Charles University, Na Slupi 4, 128 50 Prague 2, Czech Republic; michaltomcik{at}yahoo.com
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Citation

Tomcik M, Zerr P, Pitkowski J, et al
Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis
Annals of the Rheumatic Diseases 2014;73:1215-1222.

Publication history

  • Accepted April 14, 2013
  • First published May 9, 2013.
Online issue publication 
October 25, 2017

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