Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice—a translational model for atherosclerosis

L M Gierman; S Kühnast; A Koudijs; E J Pieterman; M Kloppenburg; G J V M van Osch; V Stojanovic-Susulic; T W J Huizinga; H M G Princen; A-M Zuurmond

doi:10.1136/annrheumdis-2013-203248

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Basic and translational research

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Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice—a translational model for atherosclerosis

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L M Gierman TNO, Leiden, The Netherlands Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
S Kühnast TNO, Leiden, The Netherlands Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
A Koudijs TNO, Leiden, The Netherlands PubMed articles Google scholar articles
E J Pieterman TNO, Leiden, The Netherlands PubMed articles Google scholar articles
M Kloppenburg Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
G J V M van Osch Department of Orthopaedics and Department Otorhinolaryngology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands PubMed articles Google scholar articles
V Stojanovic-Susulic Janssen, a division of Johnson & Johnson, Pharmaceutical R&D, Malvern, Pennsylvania, USA PubMed articles Google scholar articles
T W J Huizinga Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
H M G Princen TNO, Leiden, The Netherlands PubMed articles Google scholar articles
A-M Zuurmond TNO, Leiden, The Netherlands PubMed articles Google scholar articles

Correspondence to Dr A-M Zuurmond, TNO, Zernikedreef 9, P.O. Box 2215, Leiden 2301 CE, The Netherlands; Anne-Marie.Zuurmond{at}tno.nl

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Citation

Gierman LM, Kühnast S, Koudijs A, et al

Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice—a translational model for atherosclerosis

Annals of the Rheumatic Diseases 2014;73:921-927.

Publication history

Accepted April 1, 2013
First published April 26, 2013.

Online issue publication

October 25, 2017

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