Tocilizumab in patients with active rheumatoid arthritis and inadequate responses to DMARDs and/or TNF inhibitors: a large, open-label study close to clinical practice

Vivian P Bykerk; Andrew J K Östör; José Alvaro-Gracia; Karel Pavelka; José Andrés Román Ivorra; Winfried Graninger; William Bensen; Michael T Nurmohamed; Andreas Krause; Corrado Bernasconi; Andrea Stancati; Jean Sibilia

doi:10.1136/annrheumdis-2011-201087

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Tocilizumab in patients with active rheumatoid arthritis and inadequate responses to DMARDs and/or TNF inhibitors: a large, open-label study close to clinical practice

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	Abstract	Full	Pdf
May 2012	526	84	209
Jun 2012	318	120	149
Jul 2012	481	151	195
Aug 2012	139	156	117
Sep 2012	112	131	107
Oct 2012	113	101	97
Nov 2012	2474	198	363
Dec 2012	1050	237	209
Jan 2013	729	273	186
Feb 2013	317	103	109
Mar 2013	248	77	94
Apr 2013	204	35	65
May 2013	144	38	46
Jun 2013	126	33	31
Jul 2013	84	29	22
Aug 2013	116	20	29
Sep 2013	118	32	40
Oct 2013	73	27	24
Nov 2013	68	28	30
Dec 2013	51	20	21
Jan 2014	67	24	16
Feb 2014	69	22	26
Mar 2014	58	48	28
Apr 2014	72	87	28
May 2014	52	53	26
Jun 2014	47	13	17
Jul 2014	78	46	26
Aug 2014	36	32	17
Sep 2014	57	24	10
Oct 2014	52	33	20
Nov 2014	45	28	14
Dec 2014	27	40	27
Jan 2015	36	14	14
Feb 2015	31	28	21
Mar 2015	52	27	21
Apr 2015	33	25	19
May 2015	51	27	22
Jun 2015	42	22	27
Jul 2015	42	21	22
Aug 2015	47	24	21
Sep 2015	51	32	25
Oct 2015	24	11	11
Nov 2015	52	10	13
Dec 2015	37	17	14
Jan 2016	46	17	15
Feb 2016	38	13	16
Mar 2016	33	18	20
Apr 2016	62	18	15
May 2016	51	19	17
Jun 2016	26	23	11
Jul 2016	47	40	20
Aug 2016	38	17	14
Sep 2016	43	29	24
Oct 2016	83	47	75
Nov 2016	33	26	21
Dec 2016	42	31	128
Jan 2017	37	48	33
Feb 2017	27	23	12
Mar 2017	13	58	10
Apr 2017	16	42	20
May 2017	11	42	15
Jun 2017	32	31	14
Jul 2017	62	40	9
Aug 2017	107	81	23
Sep 2017	73	43	5
Oct 2017	95	45	8
Nov 2017	88	46	17
Dec 2017	78	35	15
Jan 2018	77	46	13
Feb 2018	75	33	12
Mar 2018	91	42	9
Apr 2018	73	28	9
May 2018	127	34	13
Jun 2018	70	30	7
Jul 2018	99	52	15
Aug 2018	119	30	21
Sep 2018	85	35	25
Oct 2018	80	34	18
Nov 2018	41	35	11
Dec 2018	36	32	2
Jan 2019	46	42	13
Feb 2019	34	31	10
Mar 2019	50	42	19
Apr 2019	39	38	16
May 2019	33	27	13
Jun 2019	28	26	16
Jul 2019	47	36	22
Aug 2019	38	34	15
Sep 2019	19	17	11
Oct 2019	31	27	7
Nov 2019	24	22	12
Dec 2019	23	23	11
Jan 2020	23	18	13
Feb 2020	36	30	15
Mar 2020	14	8	8
Apr 2020	25	25	18
May 2020	36	36	22
Jun 2020	33	23	22
Jul 2020	23	12	10
Aug 2020	25	21	11
Sep 2020	32	31	10
Oct 2020	27	25	16
Nov 2020	46	40	14
Dec 2020	26	24	5
Jan 2021	19	15	7
Feb 2021	18	12	14
Mar 2021	21	17	6
Apr 2021	14	11	7
May 2021	18	18	11
Jun 2021	25	24	14
Jul 2021	13	13	14
Aug 2021	24	23	19
Sep 2021	21	22	12
Oct 2021	30	20	21
Nov 2021	21	18	33
Dec 2021	17	13	6
Jan 2022	15	9	10
Feb 2022	30	30	11
Mar 2022	22	19	10
Apr 2022	35	24	17
May 2022	42	40	32
Jun 2022	37	27	20
Jul 2022	24	22	9
Aug 2022	45	40	15
Sep 2022	34	26	17
Oct 2022	44	35	18
Nov 2022	34	32	13
Dec 2022	36	33	8
Jan 2023	26	26	6
Feb 2023	40	40	5
Mar 2023	27	23	5
Apr 2023	17	15	7
May 2023	15	13	12
Jun 2023	28	22	7
Jul 2023	16	11	9
Aug 2023	13	11	10
Sep 2023	41	38	4
Oct 2023	24	22	8
Nov 2023	16	14	3
Dec 2023	57	57	5
Jan 2024	46	21	11
Feb 2024	31	23	9
Mar 2024	34	30	110
Total	12631	5431	4224

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