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  • Response to: ‘Comment on Ye et al ‘Presence of respiratory failure of COVID-19 infection in patients with rheumatism in Wuhan, China’’ by Chen et al

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Correspondence response
Response to: ‘Comment on Ye et al ‘Presence of respiratory failure of COVID-19 infection in patients with rheumatism in Wuhan, China’’ by Chen et al
  1. Jixin Zhong,
  2. Cong Ye,
  3. Shaozhe Cai,
  4. Lingli Dong
  1. Department of Rheumatology and Immunlogy, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
  1. Correspondence to Professor Jixin Zhong, Department of Rheumatology and Immunlogy, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China; zhongjixin620{at}163.com; Dr Lingli Dong, Department of Rheumatology and Immunlogy, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China; tjhdongll{at}163.com

https://doi.org/10.1136/annrheumdis-2020-218508

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    We appreciate the valuable comments from Chen et al on our recent study about the clinical characteristics of COVID-19 cases with rheumatic disease.1 They highlight an important point about the sample size of patients with rheumatism infected with COVID-19 in our study. We agree that the sample size was relatively small, although we have included all such cases in Tongji Hospital, the hospital that admitted the most patients with COVID-19 in China. We acknowledged this limitation in the discussion of the paper.2 With the urgent pandemic of COVID-19, the aim of this study is to provide a timely report to present the clinical features of patients with rheumatism infected with COVID-19. The clinical manifestation of COVID-19 cases with rheumatic disease in Wuhan, the first COVID-19 epicentre in the world, may provide important information for disease management in patients with rheumatic disease in other areas of the world. In our report, we noticed that respiratory failure was more common in patients with rheumatism (38% vs 10%, p<0.001) infected with COVID-19, although the duration of hospital stay and mortality were similar between patients with rheumatic disease and those without rheumatic disease.2 These results were confirmed by subsequent studies in other areas of the world.3 4 …

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    Footnotes

    • Handling editor Josef S Smolen

    • Contributors All authors were involved in the preparation of the manuscript and approved the final version of the manuscript.

    • Funding JZ and LD would like to acknowledge the support from the National Natural Science Foundation of China (81974254, 81670431 and 81771754) and Tongji Hospital Clinical Research Flagship Program (no. 2019CR206).

    • Competing interests None declared.

    • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting or dissemination plans of this research.

    • Provenance and peer review Not commissioned; internally peer reviewed.

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