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Hepatic manifestations of autoimmune rheumatic diseases
  1. S Abraham,
  2. S Begum,
  3. D Isenberg
  1. Centre for Rheumatology, Bloomsbury Rheumatology Unit, Department of Medicine, University College, London, UK
  1. Correspondence to:
    Professor D A Isenberg
    Centre for Rheumatology 4th Floor, Arthur Stanley House 40–50 Tottenham Street London W1T 4NJ, UK; d.isenbergucl.ac.uk

Abstract

Hepatic manifestations in autoimmune disease include chronic active hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, and nodular regenerative hyperplasia. These diseases are rare and may occur concomitantly or serially. Clinicians must be aware of the possibility of liver disease so that it can be treated as soon as possible.

  • autoimmune disease
  • hepatitis
  • cirrhosis
  • ACA, anticentromere antibodies
  • aCL, anticardiolipin antibodies
  • AMA, antimitochondrial antibodies
  • aPL, antiphospholipid antibodies
  • APS, antiphospholipid syndrome
  • CAH, chronic active hepatitis
  • DM, dermatomyositis
  • HCV, hepatitis C virus
  • LDH, lactate dehydrogenase
  • NRHL, nodular regenerative hyperplasia of the liver
  • PBC, primary biliary cirrhosis
  • PM, polymyositis
  • RA, rheumatoid arthritis
  • PSC, primary sclerosing cholangitis
  • SLE, systemic lupus erythematosus
  • SS, Sjögren’s syndrome

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