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Peripheral nerve involvement—mononeuritis,1 mononeuritis multiplex, and polyneuropathies2—has been reported in 14% of patients with giant cell arteritis (GCA).3 ,4 GCA associated with acute inflammatory demyelinating polyneuropathy (AIDP) has exceptionally been described.5 ,6 We report an unusual case of this association.
A 67 year old woman presented with a one month history of difficulty in walking, weakness, and proximal myalgia that worsened progressively. Examination showed proximal weakness and abolition of all deep tendon reflexes; there was no sensory deficit and cranial nerve function was normal. Laboratory tests disclosed normal haematological findings with an erythrocyte sedimentation rate (ESR) of 12 mm/1st h; renal and liver function tests, muscle enzymes, and thyroid stimulating hormone were in the normal range. Serum protein electrophoresis, antinuclear antibodies and rheumatoid factors, and serology for Lyme disease, Q fever, mycoplasma, Venereal Disease Research Laboratory …