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Response to: Correspondence on “Update on the diagnosis and management of systemic lupus erythematosus” by Zhou et al
  1. Antonis Fanouriakis1,
  2. Nikolaos Tziolos2,
  3. George Bertsias3,4,
  4. Dimitrios T Boumpas2
  1. 1 Department of Rheumatology, Asklepieion General Hospital, Athens, Greece
  2. 2 4th Department of Internal Medicine, "Attikon" University Hospital, Athens, Greece
  3. 3 Rheumatology, Clinical Immunology and Allergy, University of Crete School of Medicine, Iraklio, Greece
  4. 4 Laboratory of Autoimmunity-Inflammation, Institute of Molecular Biology and Biotechnology, Iraklio, Greece
  1. Correspondence to Dr Antonis Fanouriakis, Department of Rheumatology, Asklepieion General Hospital, Athens, Greece; afanour{at}

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We thank Zhou et al for their interest in our manuscript and their insightful comments.1 In figure 4 of our manuscript (Diagnostic approach to a patient with suspected systemic lupus erythematosus and the use of classification criteria to aid clinical diagnosis), we propose an algorithm to aid clinical diagnosis, especially in patients not fulfilling the classification criteria.2 As opposed to classification, diagnosis by definition may include the notion of probability (ie, possible systemic lupus erythematosus (SLE)). Moreover, as …

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  • Handling editor Josef S Smolen

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  • Contributors AF drafted and NT, GB and DTB edited the letter. All authors approved its final form.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Provenance and peer review Commissioned; internally peer reviewed.

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