Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update

Daniel Aletaha; Andreas Kerschbaumer; Kastriot Kastrati; Christian Dejaco; Maxime Dougados; Iain B McInnes; Naveed Sattar; Tanja A Stamm; Tsutomu Takeuchi; Michael Trauner; Désirée van der Heijde; Marieke Voshaar; Kevin L Winthrop; Angelo Ravelli; Neil Betteridge; Gerd-Rüdiger R Burmester; Johannes WJ Bijlsma; Vivian Bykerk; Roberto Caporali; Ernest H Choy; Catalin Codreanu; Bernard Combe; Mary K Crow; Maarten de Wit; Paul Emery; Roy M Fleischmann; Cem Gabay; Merete Lund Hetland; Kimme L Hyrich; Annamaria Iagnocco; John D Isaacs; Joel M Kremer; Xavier Mariette; Peter A Merkel; Eduardo F Mysler; Peter Nash; Michael T Nurmohamed; Karel Pavelka; Gyula Poor; Andrea Rubbert-Roth; Hendrik Schulze-Koops; Anja Strangfeld; Yoshiya Tanaka; Josef S Smolen

doi:10.1136/ard-2022-222784

Article info

Recommendation

Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update

Authors

Daniel Aletaha Division of Rheumatology, Medical University of Vienna, Wien, Austria PubMed articles Google scholar articles
Andreas Kerschbaumer Division of Rheumatology, Medical University of Vienna, Wien, Austria PubMed articles Google scholar articles
Kastriot Kastrati Division of Rheumatology, Medical University of Vienna, Wien, Austria PubMed articles Google scholar articles
Christian Dejaco Rheumatology, Medical University of Graz, Graz, Austria Rheumatology, Brunico Hospital, Brunico, Italy PubMed articles Google scholar articles
Maxime Dougados Rheumatology, Universite Paris Descartes Faculte de Medecine Site Cochin, Paris, France PubMed articles Google scholar articles
Iain B McInnes Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Naveed Sattar Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow, UK PubMed articles Google scholar articles
Tanja A Stamm Section for Outcomes Research, Medical University of Vienna, Wien, Austria PubMed articles Google scholar articles
Tsutomu Takeuchi Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine Graduate School of Medicine, Shinjuku-ku, Japan PubMed articles Google scholar articles
Michael Trauner Division of Gastroenterology and Hepatology, Medical University of Vienna, Wien, Austria PubMed articles Google scholar articles
Désirée van der Heijde Rheumatology, Leiden University Medical Center, Leiden, The Netherlands Rheumatology, Diakonhjemmet Hospital, Oslo, Norway PubMed articles Google scholar articles
Marieke Voshaar Department of Psychology, Health and Technology, Enschede, Netherlands and Stichting Tools Patient Empowerment, University of Twente, Enschede, The Netherlands PubMed articles Google scholar articles
Kevin L Winthrop Schools of Medicine and Public Health, Division of Infectious Diseases, Oregon Health & Science University, Portland, Oregon, USA PubMed articles Google scholar articles
Angelo Ravelli UO Pediatria II—Reumatologia, IRCCS Istituto Giannina Gaslini, Genova, Italy PubMed articles Google scholar articles
Neil Betteridge Neil Betteridge Associates Limited, London, UK PubMed articles Google scholar articles
Gerd-Rüdiger R Burmester Rheumatology and Clinical Immunology, Charite University Hospital Berlin, Berlin, Germany PubMed articles Google scholar articles
Johannes WJ Bijlsma Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands PubMed articles Google scholar articles
Vivian Bykerk Rheumatology, University of Toronto, Toronto, Ontario, Canada PubMed articles Google scholar articles
Roberto Caporali Department of Clinical Sciences and Community Health, ASS G. Pini, University of Milan, Milano, Italy PubMed articles Google scholar articles
Ernest H Choy CREATE Centre, Section of Rheumatology, School of Medicine, Division of Infection and Immunity, Cardiff University, Cardiff, UK PubMed articles Google scholar articles
Catalin Codreanu Rheumatology, Carol Davila University of Medicine and Pharmacy, Bucuresti, Romania PubMed articles Google scholar articles
Bernard Combe Immunorhumatologie, CHU Lapeyronie, Montpellier, France PubMed articles Google scholar articles
Mary K Crow Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York City, New York, USA PubMed articles Google scholar articles
Maarten de Wit Medical Humanities, Amsterdam University Medical Centres, Duivendrecht, The Netherlands PubMed articles Google scholar articles
Paul Emery University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK Leeds Teaching Hospitals NHS Trust, NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK PubMed articles Google scholar articles
Roy M Fleischmann Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas, USA PubMed articles Google scholar articles
Cem Gabay Division of Rheumatology, Geneva University Hospitals, Geneve, Switzerland PubMed articles Google scholar articles
Merete Lund Hetland Department of Clinical Medicine, Copenhagen University Hospital, Kobenhavn, Denmark Department of Clinical Medicine, University of Copenhagen, Kobenhavn, Denmark PubMed articles Google scholar articles
Kimme L Hyrich Centre for Epidemiology Versus Arthritis, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK PubMed articles Google scholar articles
Annamaria Iagnocco Scienze Cliniche e Biologiche, Università degli Studi di Torino, Torino, Italy PubMed articles Google scholar articles
John D Isaacs Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK PubMed articles Google scholar articles
Joel M Kremer Medicine Rheumatology, Albany Medical College, Albany, New York, USA PubMed articles Google scholar articles
Xavier Mariette Rheumatology, Assistance Publique—Hôpitaux de Paris, Paris, France Center for Immunology of Viral Infections and Auto-immune Diseases, Université Paris-Sud, Gif-sur-Yvette, France PubMed articles Google scholar articles
Peter A Merkel Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA PubMed articles Google scholar articles
Eduardo F Mysler Organización Médica de Investigación SA, Buenos Aires, Argentina PubMed articles Google scholar articles
Peter Nash Griffith University School of Medicine, Gold Coast, Queensland, Australia PubMed articles Google scholar articles
Michael T Nurmohamed Rheumatology, Amsterdam UMC Locatie VUmc, Amsterdam, The Netherlands PubMed articles Google scholar articles
Karel Pavelka Rheumatology Department, Charles University, Praha, Czech Republic PubMed articles Google scholar articles
Gyula Poor National Institute of Rheumatology & Physiology, Semmelweis University, Budapest, Hungary PubMed articles Google scholar articles
Andrea Rubbert-Roth Division of Rheumatology, Kantonsspital Sankt Gallen, Sankt Gallen, Switzerland PubMed articles Google scholar articles
Hendrik Schulze-Koops Division of Rheumatology and Clinical Immunology, Internal Medicine IV, Ludwig-Maximilians-Universitat Munchen, Munchen, Germany PubMed articles Google scholar articles
Anja Strangfeld Forschungsbereich Epidemiologie, Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany PubMed articles Google scholar articles
Yoshiya Tanaka First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan PubMed articles Google scholar articles
Josef S Smolen Division of Rheumatology, Medical University of Vienna, Wien, Austria PubMed articles Google scholar articles

Correspondence to Professor Daniel Aletaha, Division of Rheumatology, Medical University of Vienna, Wien 1090, Austria; daniel.aletaha{at}meduniwien.ac.at

View Full Text

Citation

Aletaha D, Kerschbaumer A, Kastrati K, et al

Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update

Annals of the Rheumatic Diseases 2023;82:773-787.

Publication history

Received May 12, 2022
Accepted July 18, 2022
First published August 11, 2022.

Online issue publication

October 18, 2023

Article Versions

Previous version (11 May 2023).
Previous version (11 May 2023).
Previous version (11 May 2023).
You are viewing the most recent version of this article.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Main menu

Authors

Citation

Publication history

Article Versions

Request permissions

Copyright information

Log in using your username and password

Main menu

Log in using your username and password

You are here

Authors

Citation

Publication history

Article Versions

Request permissions

Copyright information

Read the full text or download the PDF:

Log in using your username and password