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Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): what does the future hold?
  1. Murugan Sudhakar,
  2. Pandiarajan Vignesh
  1. Allergy Immunology Unit, Department of Pediatrics, PGIMER, Chandigarh, India
  1. Correspondence to Dr Pandiarajan Vignesh, Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India; vigimmc{at}

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We read with great interest the recent article by Pouletty et al, 1 a multicentre cohort from Paris, which reported an increased incidence of Kawasaki disease (KD) like presentation in association with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection (Kawa-COVID-19) in children. It is considered as a part of (Paediatric inflammatory multisystem syndrome temporally associated (PIMS-TS) with SARS-CoV-2). The varied manifestations of PIMS-TS include KD-like illness, toxic shock syndrome and multisystem failure.2–4 There is a significant difference in epidemiology and diagnostic criteria used to identify this entity compared to the usual KD (non-COVID-19 related).2–4

The annual incidence of KD in Asian populations like Japan, and Pacific Islander descent was 260 per 100 000, but in the USA, it was 25 per 100 000 children.5 Though the initial epidemic of SARS-CoV-2 infection was prevalent in Asian countries like China and South Korea, no cases of PIMS-TS or Kawa-COVID-19 were reported from these countries to date. Pouletty et al,1 in his report of 16 children with Kawa-COVID-19 illness, found that no child was from the Asian race1 (with 1.7% …

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  • Contributors MS: writing of initial draft of the manuscript, editing and revision of manuscript at all stages of its production, review of the literature. PV: inception of the manuscript’s idea and editing, critical revision of the manuscript at all stages of production and final approval.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Provenance and peer review Not commissioned; internally peer reviewed.