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Lin et al 1 raised three points with regard to residual confounding to affect our findings. Below we provide point-by-point replies to the three comments.
First, we agree that immobilisation duration is a strong risk factor for postoperative venous thromboembolism (VTE). The aim of our study was to examine the relation of incident osteoarthritis (OA) to the risk of VTE (ie, the total effect) and to assess to what extent the effect of incident OA on the risk of VTE is through its effect on knee/hip replacement (ie, the indirect effect).2 Since …
Handling editor Josef S Smolen
Correction notice This article has been corrected since it published Online First. The provenance and peer review statement has been included.
Contributors All authors have read, provided critical feedback on intellectual content and approved the final manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Provenance and peer review Commissioned; internally peer reviewed.