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We thank Gremese et al 1 for their suggestion in our research article entitled ‘Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis’.2 Their recent work described that lung perfusion CT scan identified perfusion abnormalities such as hyperperfusion around areas of hypoperfusion (leukothrombosis) in patients with COVID-19-associated pneumonia, even without respiratory distress.3 They also demonstrated that in one of these patients, lung perfusion CT scan showed an improvement in parameters related to the perfusion abnormalities according to clinical improvement after starting treatments with enoxaparin and interleukin-6 inhibitor, without steroids.1 They suggested that COVID-19-associated pneumonia might …
Footnotes
Handling editor Josef S Smolen
Contributors SA, SH, DM and AS: drafting of manuscript. SA and AS: critical review of manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Provenance and peer review Commissioned; internally peer reviewed.