Background Spondyloarthritis (SPA) is a chronic inflammatory rheumatism characterized by sacroiliitis and spinal involvement, affecting both genders but more frequent in males.
Objectives The aim of this study is to analyze the epidemiological, clinical and paraclinical characteristics of Spondyloarthritis in women.
Methods Retrospective study included 333 patients followed up for SPA at the Rheumatology Department between 2004 and 2021.
Results Our study involved 153 women and 180 men. In the female population, the mean age was 45.1 years, 12.4% had high blood pressure, 4.8% had a psychiatric comorbidity and none of the patients were smokers, versus a mean age of 36.4 years, 5% of high blood pressure’s patients, 1.7% having a psychic comorbidity and 25% of the smokers for the male with SPA. The age of onset of symptoms was 36.5 years for women versus 28 years for men (p =0.001). Axial involvement was 84.3% in women and 85% in men, while peripheral and enthesial involvement was present in 73.8% and 56.8% of female subjects and 58.8% and 46.6% of male subjects (p at 0.004 and 0.064 respectively). Coxitis was present in 13.1% and syndesmophytis in 15.3% of females versus 36.1% and 18.3% of males (p at 0.001 and 0.4 respectively). Mean erythrocyte sedimentation rate was 45.7, mean CRP 28.5 and mean calcemia 92 in the 1st group versus 43, 40.6 and 93.4 in the 2nd (p at 0.4; 0.03 and 0.03 respectively). Relapse was 26.8% in female with SPA and 12.6% in male (p =0.025)
Conclusion In our study, females SPA patients developed symptoms later than did males, peripheral and enthesial involvement is more common in females while coxitis is more common in males with statistically significant higher CRP and calcemia.
References Rusman T, van Vollenhoven RF, van der Horst-Bruinsma IE. Gender Differences in Axial Spondyloarthritis: Women Are Not So Lucky. Curr Rheumatol Rep. 2018 Jun;20(6).
Sboul S, Nassar K, Janani S. La spondylarthrite féminine: particularités cliniques et paracliniques. Revue du Rhumatisme. 2021 Dec;88:A266.
Disclosure of Interests None declared
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