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Handling editor Josef S Smolen
Contributors All authors identified the patients. DS and FF documented the patients. GS wrote the manuscript.
Funding GS is supported by the Deutsche Forschungsgemeinschaft (DFG-FOR2886 PANDORA and the CRC1181 Checkpoints for Resolution of Inflammation). Additional funding was received by the Bundesministerium für Bildung und Forschung (BMBF; project MASCARA; to GS) and the IMI funded project HIPPOCRATES (to GS and DS).
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Provenance and peer review Not commissioned; externally peer reviewed.