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Handling editor Josef S Smolen
Twitter @FragoulisGeorge, @Dr_C_Koutsianas
GEF and CK contributed equally.
Contributors Study inception: PPS. Study design: GEF, PPS and DV. Data acquisition: GEF, CK, KF, CT, SP, IM, MP, MGT and TD. Drafting the manuscript: GEF, CK, KF, CT, SP, IM, MP, MT and TD. Revising the manuscript: PPS and DV.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Provenance and peer review Not commissioned; externally peer reviewed.