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  • Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature

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Systemic lupus erythematosus
Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature

Authors

  • Patrick Coit Division of Rheumatology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Graduate Program in Immunology, University of Michigan, Ann Arbor, Michigan, USA PubMed articlesGoogle scholar articles
  • Xiavan Roopnarinesingh Graduate Program, Department of Biochemistry and Molecular Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA PubMed articlesGoogle scholar articles
  • Lourdes Ortiz-Fernández Division of Rheumatology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Kathleen McKinnon-Maksimowicz Division of Rheumatology, Henry Ford Health System, Detroit, Michigan, USA PubMed articlesGoogle scholar articles
  • Emily E Lewis Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA PubMed articlesGoogle scholar articles
  • Joan T Merrill Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA PubMed articlesGoogle scholar articles
  • W Joseph McCune Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA PubMed articlesGoogle scholar articles
  • Jonathan D Wren Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA Department of Biochemistry and Molecular Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA PubMed articlesGoogle scholar articles
  • Amr H Sawalha Division of Rheumatology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Lupus Center of Excellence, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Amr H Sawalha, Rheumatology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; asawalha{at}pitt.edu
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Citation

Coit P, Roopnarinesingh X, Ortiz-Fernández L, et al
Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature
Annals of the Rheumatic Diseases 2022;81:1428-1437.

Publication history

  • Received April 13, 2022
  • Accepted June 7, 2022
  • First published June 16, 2022.
Online issue publication 
October 18, 2023

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© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.