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Scientific Abstracts
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COVID-19
POS1245 MORTALITY OF COVID-19 IN PATIENTS WITH RHEUMATIC DISEASES: COMPARISON TO THE GENERAL POPULATION IN MÉXICO
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  1. M. U. Martínez-Martínez1,
  2. F. Irazoque-Palazuelos2,
  3. T. S. Rodriguez-Reyne3,
  4. E. Zamora4,
  5. A. Castillo Ortiz5,
  6. B. E. Zazueta6,
  7. S. Duran Barragan7,
  8. M. Rull-Gabayet3,
  9. J. F. Moctezuma-Ríos8,
  10. X. Jimenez Jimenez9,
  11. E. Martin-Nares3,
  12. D. Cervantes-Rosete3,
  13. D. Vega-Morales10,
  14. D. X. Xibille Friedmann11,
  15. A. Barragán-Garfías9,
  16. E. Alvarez Hernandez8,
  17. M. Vázquez-Del Mercado Espinosa12,
  18. C. F. Pacheco Tena13,
  19. D. Alpizar-Rodriguez14
  20. on behalf of Mexican Study group of COVID-19 in Rheumatic diseases
  1. 1Instituto Mexicano del Seguro Social, Internal Medicine, Rioverde, Mexico
  2. 2Centro de Investigación y Tratamiento Reumatológico S.C., Rheumatology, Mexico City, Mexico
  3. 3Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Immunology and Rheumatology, Mexico City, Mexico
  4. 4Centro Médico de Pensiones, Rheumatology, Merida, Mexico
  5. 5Private Practice, Rheumatology, Merida, Mexico
  6. 6Private Practice, Rheumatology, Mexicali, Mexico
  7. 7Clínica de Investigación en Reumatología y Obesidad, Rheumatology, Guadalajara, Mexico
  8. 8Hospital General de México ‘Dr. Eduardo Liceaga’, Rheumatology, Mexico City, Mexico
  9. 9Private Practice, Rheumatology, Mexico City, Mexico
  10. 10Private Practice, Rheumatology, Monterrey, Mexico
  11. 11Servicios de Salud de Morelos, Departamento de Investigación y Capacitación, Cuernavaca, Mexico
  12. 12Hospital Civil de Guadalajara “Juan I. Menchaca”, Rheumatology, Guadalajara, Mexico
  13. 13Facultad de Medicina y Ciencias Biomédicas, Rheumatology, Chihuahua, Mexico
  14. 14Colegio Mexicano de Reumatología, Research Unit, Mexico City, Mexico

Abstract

Background: COVID-19 outcomes in Mexican patients with rheumatic diseases (RDs) in comparison to general population patients are unknown.

Objectives: To compare mortality and hospitalization of COVID-19 patients with RDs and those without.

Methods: We included for this study all the Mexican patients with RDs and COVID-19 registered from April 17th to October 30th, 2020 in the COVID-19 Global Rheumatology Alliance registry. We compare clinical and demographic characteristics of patients with RDs and COVID-19 to patients with COVID-19 that were selected randomly from the Mexican Epidemiology database (1:3). A logistic regression analysis was performed to adjust for confusion variables.

Results: We included 322 patients with COVID-19 and RDs and 969 controls without RDs. Table 1 shows the demographic characteristics and comorbidities of both groups. Bivariate analysis showed that patients with RDs had higher mortality, were older, and were more frequently hospitalized. Comorbidities, such as diabetes, hypertension, cardiovascular and renal diseases were also more frequent in patients with RDs. In the multivariate analysis, having a RD was no longer associated with mortality (Figure 1).

Figure 1.
Figure 1.

Multivariate analysis of mortality

Conclusion: Patients with RDs had higher comorbidities, hospitalizations, and mortality than the general population in the bivariate analysis. However, adjusted multivariate analysis showed that the odds for mortality were not increased because of having a RD. These findings suggest that the increased mortality of Mexican patients with RDs may be explained by the higher frequency of comorbidities in this population.

View this table:
Table 1.

Comparison of patients with COVID-19 with and without RDs

Disclosure of Interests: None declared

https://doi.org/10.1136/annrheumdis-2021-eular.3447

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