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Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of scleroderma

Authors

  • Rebecca L Ross Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK Scleroderma Programme, NIHR Leeds Musculoskeletal Biomedical Research Centre, Leeds, UK PubMed articlesGoogle scholar articles
  • Clarissa Corinaldesi Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Gemma Migneco Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Ian M Carr Leeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Agne Antanaviciute Leeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Christopher W Wasson Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK Scleroderma Programme, NIHR Leeds Musculoskeletal Biomedical Research Centre, Leeds, UK PubMed articlesGoogle scholar articles
  • Antonio Carriero Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK Rheumatology Department of Lucania, Rheumatology Institute of Lucania (IReL), Potenza, Italy PubMed articlesGoogle scholar articles
  • Jörg H W Distler Department of Internal Medicine III, University of Erlangen, Erlangen, Germany PubMed articlesGoogle scholar articles
  • Steve Holmes Capella Biosciences Ltd, Cambridge, UK PubMed articlesGoogle scholar articles
  • Yasser M El-Sherbiny Department of Biosciences, Nottingham Trent University, Nottingham, Nottinghamshire, UK Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt PubMed articlesGoogle scholar articles
  • Clive S McKimmie Leeds Institute of Medical Research, Faculty of Medicine and Health, University of Leeds, Leeds, UK Virus Host Interactions Team, Section of Infection and Immunity, University of Leeds Faculty of Medicine and Health, Leeds, UK PubMed articlesGoogle scholar articles
  • Francesco Del Galdo Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK Scleroderma Programme, NIHR Leeds Musculoskeletal Biomedical Research Centre, Leeds, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Rebecca L Ross, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, LS9 7TF, UK; r.l.ross{at}leeds.ac.uk; Professor Francesco Del Galdo, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, LS9 7TF, UK; f.delgaldo{at}leeds.ac.uk
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Citation

Ross RL, Corinaldesi C, Migneco G, et al
Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of scleroderma

Publication history

  • Received June 29, 2020
  • Revised January 7, 2021
  • Accepted January 9, 2021
  • First published February 4, 2021.
Online issue publication 
June 17, 2021

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