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Crystal arthritis
Mechanosensitive TRPV4 is required for crystal-induced inflammation

Authors

  • Zhou Lan Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, Hubei, People's Republic of China PubMed articlesGoogle scholar articles
  • Lvyi Chen Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, Hubei, People's Republic of China PubMed articlesGoogle scholar articles
  • Jing Feng Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Zili Xie Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Zhiyong Liu Renmin Hospital of Wuhan University, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Fang Wang Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA Division of Dermatology, Department of Medicine, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Peng Liu School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, Hubei, People's Republic of China PubMed articlesGoogle scholar articles
  • Xueping Yue Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Lixia Du Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Yonghui Zhao Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Pu Yang Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Jialie Luo Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Zhe Zhu Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA PubMed articlesGoogle scholar articles
  • Xueming Hu Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Liang Cao Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Ping Lu Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Rajan Sah Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Kory Lavine Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Brian Kim Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA Division of Dermatology, Department of Medicine, Washington University School of Medicine in St Louis, St Louis, Missouri, USA Department of Pathology and Immunology, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  • Hongzhen Hu Department of Anesthesiology, Washington University School of Medicine in St Louis, St. Louis, Missouri, USA Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine in St Louis, St Louis, Missouri, USA Division of Dermatology, Department of Medicine, Washington University School of Medicine in St Louis, St Louis, Missouri, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Lvyi Chen, Washington University in St Louis School of Medicine, St Louis, MO 63130, USA; clyhappy05{at}163.com; Dr Hongzhen Hu; hongzhen.hu{at}wustl.edu
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Citation

Lan Z, Chen L, Feng J, et al
Mechanosensitive TRPV4 is required for crystal-induced inflammation
Annals of the Rheumatic Diseases 2021;80:1604-1614.

Publication history

  • Received March 6, 2021
  • Accepted September 13, 2021
  • First published October 18, 2021.
Online issue publication 
February 28, 2022

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© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.