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Comment on: ‘Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis’ by Sabbagh et al
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  1. Zaixing Yang1,
  2. Yan Liang2
  1. 1 Huangyan Hospital of Wenzhou Medical University, Taizhou First People’s Hospital, Taizhou, China
  2. 2 Departmentof Laboratory Diagnostics, ChangzhengHospital, Shanghai, China
  1. Correspondence to Dr Zaixing Yang, Huangyan Hospital of Wenzhou Medical University, Taizhou First People’s Hospital, Taizhou 318002, China; yangzaixingdiyi{at}163.com

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We read with great interest the article by Sabbagh et al 1 published in the Annals of the Rheumatic Diseases. We congratulate the authors for their accuracy and the exhaustive data presented, which clearly demonstrate the importance of anti-Ro52 autoantibodies in disease monitoring, management and prognosis in patients with juvenile myositis. We would like, however, to highlight some key points.

First, in this study,1 the patients with juvenile myositis including juvenile dermatomyositis (JDM), juvenile polymyositis (JPM) and juvenile connective tissue disease–myositis (JCTM) overlap are a highly heterogeneous population. In particular, JCTM added a great heterogeneity to the study population. In reality, there has been still controversy on considering CTM as a distinct entity or rather a complication …

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