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Footnotes
Handling editor Josef S Smolen
Contributors Conceptualisation: DMS and AKO. Methodology: DMS and AKO. Investigation: DMS, SB, NS-M, AB, SR, DS, PH, TR, AJ, IA and KSB. Formal analysis: DMS and SB. Writing: DMS, SB and AKO. Supervision: DLK, JDM and AKO.
Funding This study was supported by the Intramural Research Programs of the National Human Genome Research Institute, the National Institute for Allergy and Infectious Diseases, the National Institute for Arthritis and Musculoskeletal and Skin Diseases, and the NIH Transitional Program for Clinical Research.
Competing interests None declared.
Patient consent for publication Not required.
Ethics approval NIH Institutional Review Board, 94-HG-0105, IRB00000006.
Provenance and peer review Not commissioned; externally peer reviewed.