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We would like to thank Bilgin et al 1 for their interest in our paper2 and asking several questions for clarification.
First, we allowed non-steroidal anti-inflammatory drugs (NSAIDs) in this trial, except for the 6 weeks (from 2 weeks prior to the initiation of trial drugs until 4 weeks) during which NSAIDs were allowed only for fever, in order to assess the status of body temperature appropriately.
Second, the per cent change in glucocorticoid dose were compared between the placebo and tocilizumab groups by means of analysis …
Handling editor Josef S Smolen
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Not required.
Provenance and peer review Commissioned; internally peer reviewed.
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