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Handling editor Josef S Smolen
Contributors MG and MRE were involved in the design of the study and data interpretation and wrote the manuscript. MG performed the research and collected and analysed the data. MS, S-AY, ER and DM collected, verified and analysed the validation cohort. All authors reviewed and approved the manuscript’s content before submission.
Funding MG (and MRE in part) are supported by the University College London Hospital Biomedical Research Centre (BRC420).
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, conduct, reporting or dissemination plans of this research.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; externally peer reviewed.