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Systemic lupus erythematosus
Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity

Authors

  • Nikolaos I Panousis Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland Institute of Genetics and Genomics in Geneva (iG3), University of Geneva Medical School, Geneva, Switzerland Swiss Institute of Bioinformatics, Geneva, Switzerland PubMed articlesGoogle scholar articles
  • George K Bertsias Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, Medical School, Heraklion, Greece Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece PubMed articlesGoogle scholar articles
  • Halit Ongen Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland Institute of Genetics and Genomics in Geneva (iG3), University of Geneva Medical School, Geneva, Switzerland Swiss Institute of Bioinformatics, Geneva, Switzerland PubMed articlesGoogle scholar articles
  • Irini Gergianaki Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, Medical School, Heraklion, Greece Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece PubMed articlesGoogle scholar articles
  • Maria G Tektonidou Department of Propaedeutic Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece Joint Academic Rheumatology Program, National and Kapodistrian University of Athens, Medical School, Athens, Greece PubMed articlesGoogle scholar articles
  • Maria Trachana First Department of Pediatrics, Pediatric Immunology and Rheumatology Referral Center, Hippokration General Hospital, Aristotle University, Thessaloniki, Greece PubMed articlesGoogle scholar articles
  • Luciana Romano-Palumbo Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland PubMed articlesGoogle scholar articles
  • Deborah Bielser Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland PubMed articlesGoogle scholar articles
  • Cedric Howald Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland Institute of Genetics and Genomics in Geneva (iG3), University of Geneva Medical School, Geneva, Switzerland Swiss Institute of Bioinformatics, Geneva, Switzerland PubMed articlesGoogle scholar articles
  • Cristina Pamfil Department of Rheumatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania PubMed articlesGoogle scholar articles
  • Antonis Fanouriakis 4th Department of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece PubMed articlesGoogle scholar articles
  • Despoina Kosmara Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, Medical School, Heraklion, Greece Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece PubMed articlesGoogle scholar articles
  • Argyro Repa Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, Medical School, Heraklion, Greece PubMed articlesGoogle scholar articles
  • Prodromos Sidiropoulos Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, Medical School, Heraklion, Greece Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece PubMed articlesGoogle scholar articles
  • Emmanouil T Dermitzakis Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland Institute of Genetics and Genomics in Geneva (iG3), University of Geneva Medical School, Geneva, Switzerland Swiss Institute of Bioinformatics, Geneva, Switzerland Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece PubMed articlesGoogle scholar articles
  • Dimitrios T Boumpas Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece Joint Academic Rheumatology Program, National and Kapodistrian University of Athens, Medical School, Athens, Greece 4th Department of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece Medical school, University of Cyprus, Nicosia, Cyprus PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Emmanouil T Dermitzakis, Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Emmanouil.Dermitzakis{at}unige.ch; Dr Dimitrios T Boumpas, Biomedical Research Foundation of the Academy of Athens, Athens, Greece; boumpasd{at}uoc.gr
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Citation

Panousis NI, Bertsias GK, Ongen H, et al
Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity
Annals of the Rheumatic Diseases 2019;78:1079-1089.

Publication history

  • Received September 2, 2018
  • Revised March 14, 2019
  • Accepted March 16, 2019
  • First published June 5, 2019.
Online issue publication 
May 13, 2021

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.