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We read with great interest the study published by Moltó et al on the impact of concomitant fibromyalgia (FM) on tumor necrosis factor (TNF) alpha blockers’ effectiveness in axial spondyloarthritis (axSpA).1 Indeed, this is a challenging problem in daily practice, especially considering the difficulties in differentiating enthesitis and FM symptoms.2 Therefore, we would like to raise some issues that need clarification in order to better understand the relevance of the study.
In the published paper, data on the history of antidepressant, third-ladder analgesic and nonsteroidal anti-inflammatory drug (NSAID) intake in patients enrolled are extensively reported. The results indicate that the use of …
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