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Handling editor Josef S Smolen
Contributors LF, IN and IP: contributed to the concept and design of the work; acquisition, analysis and interpretation of data for the work; participated in the drafting of the work and revised it for important intellectual content; and gave final approval of the version to be published.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Ethics approval National Health Service South-East Multicentre Research Ethics Committee.
Provenance and peer review Not commissioned; externally peer reviewed.
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