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Osteoarthritis
microRNA-181a-5p antisense oligonucleotides attenuate osteoarthritis in facet and knee joints

Authors

  • Akihiro Nakamura Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada Division of Rheumatology, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Yoga Raja Rampersaud Arthritis Program, University Health Network, Toronto, Ontario, Canada Department of Surgery, University of Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Sayaka Nakamura Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada PubMed articlesGoogle scholar articles
  • Anirudh Sharma Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada PubMed articlesGoogle scholar articles
  • Fanxing Zeng Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada PubMed articlesGoogle scholar articles
  • Evgeny Rossomacha Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada PubMed articlesGoogle scholar articles
  • Shabana Amanda Ali Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada PubMed articlesGoogle scholar articles
  • Roman Krawetz McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada PubMed articlesGoogle scholar articles
  • Nigil Haroon Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada Division of Rheumatology, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Anthony V Perruccio Arthritis Program, University Health Network, Toronto, Ontario, Canada Department of Surgery, University of Toronto, Ontario, Canada Institute of Health Policy, Management & Evaluation, Dalla Lana School of Public Health, University of Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Nizar N Mahomed Arthritis Program, University Health Network, Toronto, Ontario, Canada Department of Surgery, University of Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Rajiv Gandhi Arthritis Program, University Health Network, Toronto, Ontario, Canada Department of Surgery, University of Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Jason S Rockel Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada PubMed articlesGoogle scholar articles
  • Mohit Kapoor Arthritis Program, University Health Network, Toronto, Ontario, Canada Division of Genetics and Development, Krembil Research Institute, University Health Network, Toronto , Ontario, Canada Department of Surgery, University of Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Mohit Kapoor, Arthritis Program, University Health Network, Department of Surgery and Department of Laboratory Medicine and Pathobiology, University of Toronto, Division of Genetics and Development, Krembil Research Institute, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada; mkapoor{at}uhnresearch.ca
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Citation

Nakamura A, Rampersaud YR, Nakamura S, et al
microRNA-181a-5p antisense oligonucleotides attenuate osteoarthritis in facet and knee joints
Annals of the Rheumatic Diseases 2019;78:111-121.

Publication history

  • Received April 19, 2018
  • Revised August 31, 2018
  • Accepted September 3, 2018
  • First published October 4, 2018.
Online issue publication 
December 18, 2018

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© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.